POLAKOF Sergio's profile
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POLAKOF SergioORCID_LOGO

  • Human Nutrition Unit, INRAE-Université Clermont-Auvergne, Clermont-Ferrand, France
  • biology, human nutrition, metabolism, omics, physiology, precision nutrition
  • recommender, manager

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Areas of expertise
I obtained his PhD in 2008 at the University of Vigo (Spain). Following several years dedicated to comparative physiology and nutrition research, my focus shifted towards human nutrition and metabolism. Currently, my primary research interest lies in comprehending how the human body adapts to nutritionally induced metabolic diseases associated with aging, such as obesity, diabetes, and metabolic syndrome. I aim to achieve this by identifying and predicting the phenotypic responses derived from metabolomics that occur at the onset of dysmetabolism. My research encompasses two main areas: - To enhance the characterization and prediction of phenotypes, along with their biomarkers, that progress from a healthy state to a pathophysiological status. This is crucial for developing preventive nutritional strategies. My approach heavily relies on metabolomics-based phenotyping in clinical studies (including cohorts and interventional studies) as well as pre-clinical models, with a particular focus on multi-catheterized minipigs. - To gain insights into the inter-individual variability in responses to food within the context of metabolic diseases. This deep phenotyping approach aims to create personalized nutrition strategies, particularly as individuals age.
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POLAKOF SergioORCID_LOGO

  • Human Nutrition Unit, INRAE-Université Clermont-Auvergne, Clermont-Ferrand, France
  • biology, human nutrition, metabolism, omics, physiology, precision nutrition
  • recommender, manager

Recommendations:  0

Reviews:  0

Areas of expertise
I obtained his PhD in 2008 at the University of Vigo (Spain). Following several years dedicated to comparative physiology and nutrition research, my focus shifted towards human nutrition and metabolism. Currently, my primary research interest lies in comprehending how the human body adapts to nutritionally induced metabolic diseases associated with aging, such as obesity, diabetes, and metabolic syndrome. I aim to achieve this by identifying and predicting the phenotypic responses derived from metabolomics that occur at the onset of dysmetabolism. My research encompasses two main areas: - To enhance the characterization and prediction of phenotypes, along with their biomarkers, that progress from a healthy state to a pathophysiological status. This is crucial for developing preventive nutritional strategies. My approach heavily relies on metabolomics-based phenotyping in clinical studies (including cohorts and interventional studies) as well as pre-clinical models, with a particular focus on multi-catheterized minipigs. - To gain insights into the inter-individual variability in responses to food within the context of metabolic diseases. This deep phenotyping approach aims to create personalized nutrition strategies, particularly as individuals age.